Editor-in-Chief Hatice Kübra Elçioğlu Vice Editors Levent Kabasakal Esra Tatar Online ISSN 2630-6344 Publisher Marmara University Frequency Bimonthly (Six issues / year) Abbreviation J.Res.Pharm. Former Name Marmara Pharmaceutical Journal
Marmara Pharmaceutical Journal 1991 , Vol 7 , Issue 2
Analysis of acetaminophen and Phenobarbital combinations by nonaqueous titration
Gönül Kunt,Cemal Özeroğlu,A. Sezai Saraç
The difference in pKa values of acetemimophen and phenobarbital permits differentiation of mixtures containing these drugs. Titrations are performed nonaqueously using tetrabutylammonium hydroxide as the titrant. End-points were determined potentiometrically using a platiniuö-calomel electrode system. Methylisobutylketon and methylethyl keton were evaluated as solvent for the titration. Keywords :
Marmara University