Editor-in-Chief Hatice Kübra Elçioğlu Vice Editors Levent Kabasakal Esra Tatar Online ISSN 2630-6344 Publisher Marmara University Frequency Bimonthly (Six issues / year) Abbreviation J.Res.Pharm. Former Name Marmara Pharmaceutical Journal
Journal of Research in Pharmacy 2022 , Vol 26 , Issue 6
Pharmaceutical, biological agents, and vaccines under clinical trials for COVID-19 and roles of pharmacists to combat COVID-19, an update
Mari Kannan MAHARAJAN1,Kingston RAJIAH2,Bharath POGULA3,Sridevi CHIGURUPATI4,Sujitha KATRAGADDA5
1School of Pharmacy, University of Nottingham Malaysia, Selangor, Malaysia
2Department of Pharmacy, GITAM School of Pharmacy, GITAM Deem to be University, Hyderabad, India
3Research and Development, GVB Biopharma, Grass Valley, Oregon, United States of America
4Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, Qassim University, Buraydah, Kingdom of Saudi Arabia
5Pharmacist, Walgreens, Columbus, Ohio, United States of America
DOI : 10.29228/jrp.246 Due to the high mortality rate and rapid spread in the early phase of the COVID-19 pandemic, the healthcare system used various treatment options. The pathology associated with COVID-19 includes inflammatory responses which ultimately lead to multi-system organ failure or “cytokines storm”. Treating COVID-19 at the initial stage of pandemic has become a challenge as there are no medications that have yet been approved by the FDA or other regulatory agencies. There are many medications have been used by the practitioners to combat the severity of the inflammatory responses. This article summarized the repurposed medications that have received attention during the COVID-19 pandemic and provided an outline of the therapeutic agents, which are under clinical trial that may be helpful to treat COVID-19. This article also emphasizes on pharmacist roles and responsibilities during disasters and pandemics and discussed various vaccines undergoing clinical trials currently. Keywords : Biological agents; Clinical Trials; Coronavirus; Pharmacist; Therapeutic agents; Vaccines
Marmara University