Editor-in-Chief Hatice Kübra Elçioğlu Vice Editors Levent Kabasakal Esra Tatar Online ISSN 2630-6344 Publisher Marmara University Frequency Bimonthly (Six issues / year) Abbreviation J.Res.Pharm. Former Name Marmara Pharmaceutical Journal
Journal of Research in Pharmacy 2022 , Vol 26 , Issue 4
Formulation and evaluation of herbal antioxidant face cream using extract of the marine seaweed Sargassum spp. (Phaeophyceae)
1Department of Coastal environment, Faculty of Basic and Marine Sciences, The University of Jordan, Aqaba, Jordan
2Department of Marine Biology, Faculty of Basic and Marine Sciences, The University of Jordan, Aqaba, Jordan
3Department of Pharmacy, Faculty of Pharmacy, Amman Arab University, Amman, Jordan
DOI : 10.29228/jrp.180 The present study develops a formulation of face cream which is made by the ethanol extract of Sargassum spp. (Phaeophyceae) from the Jordanian Gulf of Aqaba. A different type of formulations (from F1 to F8), such as oil in water were discovered to obtain the best formula of a cosmetic cream of marine herbal origin. The evaluation of all formulations (F1 to F6) has been done by the analysis of different parameters like viscosity, spread ability and stability. An ethanol fraction analyzed from a sample of Sargassum spp. showed that F2, F3, F6 and F7 were of the best homogeneity. These formulas were the subject of further evaluation tests. By implementing the dye test to formulas F2, F3, F6 and F7, all were showed a O/W feature of emulsion. The evaluation of formulations of F3, F4, F6 and F7 was conducted by using an accelerated test. Parameters including homogeneity, appearance, type of smear and removal were tested and showed acceptable stability. Among the eight formulations (F1-F8), only F2 and F6 showed the best results in terms of stability, texture and evaluation test. F2 and F6 are held intact with good appearance and consistency that continues until day 15 after preparation. Hence, the study suggests that the composition of extract and the base of the cream F2 and F6 are more stable and safer. Keywords : Herbal cosmetics; emulsions; formulation; Sargassum spp.; phaeophyceae; Gulf of Aqaba
Marmara University