Editor-in-Chief Hatice Kübra Elçioğlu Vice Editors Levent Kabasakal Esra Tatar Online ISSN 2630-6344 Publisher Marmara University Frequency Bimonthly (Six issues / year) Abbreviation J.Res.Pharm. Former Name Marmara Pharmaceutical Journal
Journal of Research in Pharmacy 2023 , Vol 27 , Issue 4
Anti-arthritic Activity of Senna auriculata Leaves Extract on Formaldehyde-Induced Arthritic Rats
Shubhangi SUTAR1,Snehal KORPALE1,Sameer NADAF2,Santosh GHULE1,Sachinkumar PATIL1
1Department of Quality Assurance, Ashokrao Mane College of Pharmacy, PethVadgaon, Tal-Hatkanangle, Dist Kolhapur. 416112, India
2Sant Gajanan Maharaj College of Pharmacy, Mahagaon, Site: Chinchewadi, Maharashtra 416503, India
DOI : 10.29228/jrp.427 Since ancient days, herbal medicines are serving humankind. Consequently, most therapeutic agents developed are of plant origin. Senna auriculata is highly valued in Indian drugs for managing painful inflammation and diabetes. This study aimed to measure the anti-inflammatory potential of Senna auriculata leaf extract. The anti-arthritis activity was evaluated using Inhibition % of paw edema, Haemoglobin Estimation, C-reactive protein (CRP) detection, and radiography. The % of inhibition was compared with the standard drug. Phytochemical investigation indicates the presence of various phytoconstituents like alkaloids, flavonoids, tannins, steroids, and Anthraquinone and Saponin Glycosides. Senna auriculata leaves extract inhibition of paw volume and swelling. Keywords : Senna auriculata; Phytochemical analysis; Anti-inflammatory activity; C-reactive protein detection
Marmara University